How We Can Support the Drug Development Pipeline

TISSUE SOURCING

 It is well known that attrition rates in drug development are high, and any methodology which can decrease this is a welcome asset. Integrating human tissue research into drug discovery and development programs can provide clearer answers as to whether NCEs are likely to cause adverse reactions or are likely to succeed in the clinic.
Efficacy and safety are two key aspects of an NCE profile which must be fulfilled before they can be submitted for clinical evaluation. Evidence of likely clinical effectiveness is a milestone decision for a drug company to take an NCE into the clinic, with regulatory authorities looking at safety, ensuring that the appearance of toxic side effects in patient populations is minimised.
To help with these decisions, and enable their partners to progress as swiftly as possible to clinical trials, Source BioScience provides an expertise in human tissue based studies including cross reactivity and biomarker assay development and validation.
Source BioScience is licensed by the HTA to handle and store human tissue. We have a comprehensive bank with a range of normal and disease tissue types from a range of organs together with demographic history.
We use this tissue to support studies for our clients. We can also use our network of tissue providers to source fully consented tissue to meet the demands of your study.
Source BioScience can also advise and support you in the development of suitable protocols to test NCEs in tissue to provide comprehensive data to satisfy FDA requirements, including incorporation of suitable controls to add statistical power to your study.

Use Source BioScience because:

• We are an established tissue provider for NCE studies.
• We have many years experience in tissue handling and protocol development for cross reactivity and biomarker assay development and validation.
• We are fully licensed by the HTA to store tissue from your studies for later analysis.
• Our experience means that we can quickly set up and carry out studies to meet your deadlines and cut development times and costs.
• Our network of tissue providers means that you do not have to waste time searching for the right partner. Source BioScience has an established network in place ready to meet your demands.

For further information or to discuss your project, please contact us at: pharma.