How We Can Support the Drug Development Pipeline

Roche AmpliChip™

 Source BioScience offers CYP450 testing to support preclinical and clinical trial studies helping to enrich patient populations for clinical trials and optimising drug treatment regimes.
The AmpliChip® CYP450 test is the FIRST pharmacogenetic microarray-based test which is FDA and IVD approved for clinical use.
The test identifies a patient's CYP2D6 & CYP2C19 genotype by analysing DNA extracted from a whole blood sample. These two genes influence the metabolism of commonly prescribed drugs (~25%) including antidepressants, antipsychotics and ADHDs along with other medications.
The AmpliChip CYP450 test can predict phenotypes based on genotype, stratifying patients according to their profiles to ensure the best therapeutic results.

Benefits:

• Robust and accurate results
  Sensitivity for normal CYP2D6 & CYP2C19 alleles is 100%
  Sensitivity for 33 CYP2D6 alleles is 99.2%
  Sensitivity for 3 CYP2D19 alleles is 100%
• Unparalleled characterization
• Identifies CYP2D6 duplications and deletions
• Software generates customized reports for both phenotype and genotype

Source BioScience is a preferred UK service supplier.

Please note that Source BioScience provides a range of mutation analysis tests for drugs with a recommendation in their labelling for genetic testing. For further information please click here.

Why use Source BioScience?

• Quality: Rapid turnaround and accurate results. All data is sent in strictest confidence to you on CD-ROM, e-mail or web server. We are also GLP,GCP ,CPA accredited and a UK preferred service supplier for ABI and Roche.
• Pricing: Our high throughput reduces unit labour and capital costs meaning we can offer exceptional value for money. Furthermore, savings are made by bulk purchase of reagents.
• Personal Touch: We can also design, validate and genotype user-defined SNPs.
• Commitment to improvement:We are continuously introducing new technologies to reduce costs, shorten timelines and reduce consumables including amounts of your DNA.

Contact:
Email: pharma
Telephone: +44(0) 115 973 9012